Amines and amides are two types of compounds found in the field of organic chemistry. Both types are made up of nitrogen atoms along with other atoms. But amines and amides have specific characteristics and properties. The main difference between amine and amide is the presence of a carbonyl group in their structure. Amines have no carbonyl group attached to the nitrogen atom. Whereas amides have a carbonyl group attached to a nitrogen atom.
An amine is a derivative of ammonia. It is composed of one or more alkyl groups that replace hydrogen atoms in ammonia (NH). Whereas amides are organic compounds that contain a nitrogen group directly attached to a nitrogen atom. Amides can also be classified as aliphatic and aromatic amides. So, in today’s article, we will tell you the information about Amine vs Amide.
Difference Between Amine and Amide
|An amine is an organic compound composed of one or more nitrogen atoms bonded to an alkyl group.||An amide is an organic compound composed of a dissociated ammonium group with an acyl group.|
|Amines are made up of C, H and N atoms.||Amides are made up of C, H, N and O atoms.|
|There are no carbonyl groups in the structure of amines.||Amides have carbonyl groups.|
|Amines are gases at room temperature or easily vaporize.||Amides are solid at room temperature.|
|Amines show basic.||Amide shows acidic characteristics.|
|Amines have relatively low boiling points.||Amides have relatively high boiling points.|
What is an Amine?
An amine is a derivative of ammonia. It is composed of one or more alkyl groups. which replace hydrogen atoms in ammonia (NH3) molecule. Hence the base group is directly attached to the nitrogen atom. According to the number of base groups that have been attached to the nitrogen atom. /Amines are classified into three broad groups. Primary and secondary amines have H atoms. It is directly bound to the nitrogen atom.
Primary Amine – An alkyl group attached to the nitrogen atom.
Secondary Amines – Two alkyl groups are attached to the nitrogen atom.
Tertiary amines – three alkyl groups attached to the nitrogen atom.
Primary and secondary amines are capable of having hydrogen bonds. Tertiary amines have no H atoms to form hydrogen bonds. But all amine types can have intermolecular hydrogen bonds with water (H2O) due to the presence of a lone electron pair on the nitrogen atom. Therefore amines with low molecular weight can be dissolved in water.
What is an Amide?
Amide is a derivative of carboxylic acid. Therefore they have a carbonyl carbon with an attached R group. and has a -NH2 group directly attached to the carbonyl carbon. There is no substituent on the nitrogen added to the end of the common name of the corresponding acid. If there are alkyl groups attached to the nitrogen atom, then, those groups are named after the substituents. Nitrogen does not exist on or are able to form hydrogen bonds with one substance to another.
Classification of amides
Elementary cations – nitrogen atom not attached to any alkyl group
Secondary amide – nitrogen atom attached to a single alkyl group
Tertiary amide – nitrogen atom attached to two alkyl groups
Amides are derived from deprotonated ammonia. This deprotonated ammonia can be attached to an acyl group (R-C=O) and form an amide. Amides are also formed from carboxylic acids. There, the hydroxyl group (-OH) of the carboxylic acid is replaced with deprotonated ammonia.
Similarities Between Amine and Amide
Amines and amides are classified into aliphatic and aromatic compounds based on the presence or absence of a ring structure.
Amines and amides are soluble in water due to the presence of a -NH group.
These -NH groups can form intermolecular hydrogen bonds with water molecules.
Amines and amides are also classified as primary, secondary or tertiary compounds according to the number of alkyl groups attached to the nitrogen atom.
What is The Difference Between An Amide And an Amine?
- An amine is an organic compound composed of one or more nitrogen atoms bonded to alkyl groups.
- An amide is an organic compound composed of a deprotonated ammonium group with an acyl group.
- There is no carbonyl group in the structure of amines. Whereas amides contain carbonyl groups.
- Amines are made up of C, H and N atoms. Whereas amides are made up of C, H, N and O atoms.
- Amines show originality. Whereas amides show acidic characteristics.
- Most low molecular weight amines are gases at room temperature or vaporize easily.
- Most amides are solid at room temperature.
- Amines have a relatively low boiling point. Whereas amides have relatively high boiling points.
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